UNMET NEEDS IN TREATING ITCH: REACHING BEYOND ECZEMA

Unmet needs in treating itch: reaching beyond eczema

Purpose Pruritus is an unpleasant sensation that creates the urge to scratch.In many chronic conditions, relentless pruritus and scratching perpetuates a vicious itch-scratch cycle.Uncontrolled itch can detrimentally affect quality of life and may lead to sleep disturbance, impaired concentration, financial burden, and psychological suffering.Recen

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Desmantling patriarchy: political practices and Spanish feminist movement slogans in the democratic transition

The feminist movement in Spain arrived to Tongue Depressors its highest development in the seventies with the beginning of the democratic transition.The transitional process represented an opportunity for the vindication of the rights of women an established the new bases on the place they should represent in the future democratic society, and also

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The role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress through regulating pyruvate kinase M2 ubiquitination

Abstract NAD-dependent deacetylase Sirt2 is involved in mammalian metabolic activities, matching energy demand with energy production and expenditure, and is relevant to a variety of metabolic diseases.Here, we constructed Sirt2 knockout and adeno-associated virus overexpression mice and found that deletion of hepatic Sirt2 accelerated primary obes

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